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Development of a men's Preference for Testosterone Replacement Therapy (P-TRT) instrument
Sheryl L Szeinbach1, Enrique Seoane-Vazquez, Kent H Summers
1Ohio State University, College of Pharmacy, Columbus, OH, USA.
Patient Preference and Adherence
|September 13, 2012
Summary
This study developed the Preference for Testosterone Replacement Therapy (P-TRT) instrument using qualitative interviews. The P-TRT instrument helps understand patient preferences for TRT, with most men preferring topical gels.
Area of Science:
- Endocrinology
- Men's Health
- Psychometrics
Background:
- Testosterone replacement therapy (TRT) is used to treat low testosterone.
- Understanding patient preferences is crucial for treatment adherence and effectiveness.
- A validated instrument for assessing TRT preferences was lacking.
Purpose of the Study:
- To develop a conceptual model of patient preferences for TRT.
- To create and validate the Preference for Testosterone Replacement Therapy (P-TRT) instrument.
Main Methods:
- Qualitative interviews with 58 male TRT users.
- Thematic analysis of interview data using NVivo 9.
- Cognitive debriefing to refine the conceptual model and P-TRT instrument.
Main Results:
- A conceptual model with eight dimensions of TRT preference was developed.
- The 29-item P-TRT instrument was created and validated.
- Most men preferred topical gel formulations over injections or patches.
Conclusions:
- The P-TRT instrument aligns with the conceptual model and is suitable for clinical use.
- The study provides insights into patient preferences for TRT products.
- The P-TRT instrument can aid in personalized TRT selection and management.
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