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A synergistically enhanced T(1) -T(2) dual-modal contrast agent
Zijian Zhou1, Dengtong Huang, Jianfeng Bao
1State Key Laboratory of Physical Chemistry of Solid Surfaces, The Key Laboratory for Chemical Biology of Fujian Province and Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China.
None:
Monodisperse Gd(2) O(3) -embedded iron oxide (GdIO) nanoparticles can simultaneously enhance the local magnetic field intensities of each other under an external magnetic field and result in synergistic enhancement of T(1) and T(2) effects. GdIO nanoparticles have the unique property to be both T(1) and T(2) contrast agents and can potentially lead to higher accuracy in cancer diagnosis, particularly liver tumors.
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