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Related Concept Videos

Adult Stem Cells01:33

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...
Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...

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Isolating Stem Cells from Soft Musculoskeletal Tissues
07:49

Isolating Stem Cells from Soft Musculoskeletal Tissues

Published on: July 5, 2010

Stem cells, dot-com.

Bryan A Liang1, Tim K Mackey

  • 1Institute of Health Law Studies, California Western School of Law, San Diego, CA 92101, USA. baliang@alum.mit.edu

Science Translational Medicine
|September 14, 2012
PubMed
Summary
This summary is machine-generated.

Direct-to-consumer stem cell treatments pose global health risks due to limited approval and unclear regulation. Clearer authority and international frameworks are needed to protect consumers from unproven therapies.

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Published on: February 20, 2012

Area of Science:

  • Biomedical Regulation
  • Public Health
  • Regenerative Medicine

Background:

  • The internet has facilitated direct-to-consumer (DTC) advertising for unproven stem cell treatments.
  • These treatments are marketed for various conditions despite limited regulatory approval, posing significant public health and safety risks.
  • Uncertainty exists regarding whether these stem cell uses fall under existing drug or biologic regulations.

Purpose of the Study:

  • To highlight the regulatory ambiguity surrounding DTC stem cell therapies.
  • To advocate for enhanced regulatory oversight and international collaboration.
  • To emphasize the need for consumer protection measures in the context of stem cell treatments.

Main Methods:

  • This study is a policy and regulatory analysis.
  • It examines the current landscape of direct-to-consumer stem cell marketing.
  • It reviews existing regulatory frameworks and identifies gaps.

Main Results:

  • Direct-to-consumer stem cell therapies are widely marketed online with minimal regulatory oversight.
  • There is a lack of clarity on whether these products are regulated as drugs or biologics.
  • This regulatory gap creates significant risks for patient safety and public health.

Conclusions:

  • Regulatory agencies require clear authority to oversee stem cell treatments.
  • An international framework is essential for standardizing the appropriate use of stem cells.
  • Consumer protection laws must be leveraged to scrutinize providers of unproven stem cell therapies.