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Updated: May 18, 2026

21:16
An In Vitro Skin Irritation Test (SIT) using the EpiDerm Reconstructed Human Epidermal (RHE) Model
Published on: July 13, 2009
Assessment of in vitro skin irritation potential of nanoparticles: RHE model
P Balakrishna Murthy1, A Sairam Kishore, P Surekha
1International Institute for Biotechnology and Toxicology (IIBAT), Kancheepuram, Tamil Nadu, India. director@iibat.com
Methods in Molecular Biology (Clifton, N.J.)
|September 15, 2012
Abstract:
The skin irritation test is designed for the prediction of acute skin irritation of nanoparticles by measurement of its cytotoxic effect, as reflected in the MTT assay, on the Reconstructed Human Epidermis (RHE) model. RHE tissues are commercially available.

