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Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
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Depressive symptoms and childhood sleep apnea syndrome

Marco Carotenuto1, Maria Esposito, Lucia Parisi

  • 1Sleep Clinic for Developmental Age, Clinic of Child and Adolescent Neuropsychiatry, Second University of Naples, Naples, Italy.

Neuropsychiatric Disease and Treatment
|September 15, 2012
PubMed

Insights

Sleep-related breathing disorders (SRBD) are linked to higher depression scores in children. Assessing mood in children with SRBD is crucial for early intervention and better health outcomes.

Area of Science:

  • Pediatric Sleep Medicine
  • Child Psychiatry
  • Respiratory Medicine

Background:

  • The link between sleep disturbances and mood regulation is established.
  • Sleep-related breathing disorders (SRBD) are increasingly suspected in the development of childhood depression.
  • However, conclusive clinical data remain limited.

Purpose of the Study:

  • To investigate the association between SRBD and depressive symptoms in school-aged children.
  • To identify potential risk factors for depression in children with SRBD.

Main Methods:

  • A cohort of 94 children with SRBD and 107 healthy children was studied.
  • Overnight respiratory evaluation assessed SRBD severity (apnea-hypopnea index, oxygen desaturation index).
  • The Italian version of the Children Depression Inventory (CDI) screened for depressive symptoms.

Main Results:

  • Children with SRBD exhibited significantly higher CDI scores compared to controls.
  • CDI scores positively correlated with apnea-hypopnea index and oxygen desaturation index.
  • An apnea-hypopnea index ≥ 3 and oxygen desaturation index ≥ 1 were identified as risk factors for depressive symptoms.

Conclusions:

  • Mood assessment is vital for children diagnosed with SRBD.
  • Early identification of depressive symptoms in this population may improve management.
Abstract

Keywords:
cardiorespiratory monitoringchildrendepressionsleep-related breathing disorders

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