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Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice
Published on: February 20, 2019
Biochemical indicators of atherogenic and protective activity of xydiphone in experimental animals
E A Yur'eva1, V S Sukhorukov, A N Murashov
1Moscow Research Institute of Pediatrics and Pediatric Surgery, Moscow, Russia. trodina@pedklin.ru
Bulletin of Experimental Biology and Medicine
|September 15, 2012
Abstract:
Atherosclerotic plaque formation and vascular calcinosis were modeled in a subchronic experiment. Reduced HDL and elevated LDL concentrations, increased atherogenic index and albumin toxicity index, and high blood levels of triglycerides and uric acid were early markers of pathology. Xydiphone in combination with vitamin D effectively reduced these changes and the degree of vascular calcinosis.
