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Cross-imaging system comparison of backscatter coefficient estimates from a tissue-mimicking material
Kibo Nam1, Ivan M Rosado-Mendez, Lauren A Wirtzfeld
1Department of Medical Physics, University of Wisconsin, 1111 Highland Avenue, Madison, Wisconsin 53705, USA.
The Journal of the Acoustical Society of America
|September 18, 2012
Summary
Quantitative ultrasound techniques are crucial for clinical applications. This study demonstrates accurate ultrasonic backscatter coefficient (BSC) estimation across different clinical ultrasound systems, validating its clinical implementation.
Area of Science:
- Medical Imaging
- Biomedical Engineering
- Acoustics
Background:
- Quantitative ultrasound (QUS) techniques require accurate parameter estimation.
- Ultrasonic backscatter coefficient (BSC) is a key QUS parameter.
- Previous studies showed agreement in BSC estimates using laboratory systems.
Purpose of the Study:
- To compare BSC estimates from a tissue-mimicking sample using four clinical ultrasound scanners.
- To validate BSC estimation independent of the clinical imaging system.
Main Methods:
- RF echo data (1-15 MHz) were acquired from a characterized sample using four clinical scanners.
- A reference phantom was used for analysis.
- BSC estimates were compared across scanners and with prior laboratory measurements.
Main Results:
- Excellent quantitative agreement in BSC estimates was observed across the four clinical array-based imaging systems.
- Clinical system BSC estimates agreed with theoretical predictions.
- Clinical estimates also matched laboratory measurements using single-element transducers.
Conclusions:
- Clinical ultrasound systems can accurately estimate the ultrasonic backscatter coefficient (BSC).
- BSC estimation is demonstrated to be independent of the specific clinical imaging system used.
- This finding supports the clinical implementation of quantitative ultrasound techniques.
