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Related Experiment Video

Updated: Apr 3, 2026

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

Parathyroid carcinoma.

Waqas Tariq Butt¹, Asad Azim, Ansab Abbas

¹East Surgical Ward, King Edward Medical University / Mayo Hospital, Lahore. wtbutt@hotmail.com

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

|September 18, 2012

Summary

This summary is machine-generated.

Parathyroid carcinoma, a rare endocrine cancer, can present insidiously with symptoms like kidney stones and bone disease. This case highlights delayed diagnosis and management of this rare malignancy.

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Area of Science:

Endocrinology
Oncology
Pathology

Background:

Parathyroid carcinoma is an extremely rare endocrine malignancy, representing less than 1% of primary hyperparathyroidism cases.
Hyperparathyroidism can lead to significant renal and musculoskeletal complications if left untreated.

Observation:

A middle-aged woman presented with a 3-year history of undiagnosed primary hyperparathyroidism, manifesting as renal stones and advanced bone disease.
Pre-operative localization studies guided a focused cervical exploration and parathyroidectomy.

Findings:

Postoperative histopathology confirmed parathyroid carcinoma.
The patient is currently under surveillance with stable parathyroid hormone levels, without requiring further surgical intervention.

Implications:

This case underscores the importance of considering rare diagnoses in persistent hyperparathyroidism.
Early detection and appropriate management are crucial for improving outcomes in parathyroid carcinoma.
This report adds to the limited literature on parathyroid carcinoma in Pakistan.