[Ultrastructural features of erythropoiesis disorder in Rauscher virus leukemia]

The population of leukemic cells (beginning from the precursor cells) has been identified by electron-microscopy methods. Ultrastructural changes typical of the erythropoiesis alteration are determined. Peculiarities in the formation of a leukemic cells population in different hemopoietic organs and changes in erythroid islands (the main morphofunctional unit of erythropoiesis) are revealed. Data obtained show the significant disturbances in differentiation of erythroid cells in the virus leukoses and are very important form the further study of the leukemogenesis mechanisms.