Update on imaging for suspected renovascular hypertension in children and adolescents

Stephen D Marks1, Kjell Tullus

  • 1Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK. stephen.marks@gosh.nhs.uk

Current Hypertension Reports
|September 19, 2012
PubMed

Insights

Renovascular disease is a key consideration in children with high blood pressure, even with obesity. Early detection through advanced imaging can lead to effective treatment for these young patients.

Area of Science:

  • Pediatric Nephrology
  • Cardiovascular Research
  • Medical Imaging

Background:

  • Childhood obesity is increasing primary hypertension in developed nations.
  • Renovascular disease is a critical, yet often overlooked, cause of hypertension in children.
  • Identifying renovascular disease offers a treatable pathway for pediatric hypertension.

Purpose of the Study:

  • To investigate the prevalence and diagnostic approaches for renovascular disease in pediatric hypertension.
  • To highlight the importance of considering renovascular disease in children with uncontrolled hypertension.
  • To evaluate current imaging modalities for diagnosing renovascular disease.

Main Methods:

  • Review of diagnostic imaging techniques including Doppler renal ultrasonography, computed tomography angiography (CTA), and magnetic resonance angiography (MRA).
  • Emphasis on digital subtraction angiography as the gold standard for diagnosis.
  • Clinical identification criteria such as poor blood pressure control despite multiple medications or associated syndromes.

Main Results:

  • Advances in Doppler ultrasonography, CTA, and MRA have improved detection capabilities.
  • Digital subtraction angiography remains the definitive diagnostic tool.
  • Renovascular disease is a treatable cause of hypertension in pediatric patients.

Conclusions:

  • Renovascular disease should be actively investigated in children with difficult-to-control hypertension.
  • Digital subtraction angiography is crucial for both diagnosis and potential therapeutic intervention.
  • Timely diagnosis and treatment of renovascular disease can significantly improve outcomes in pediatric hypertension.

Related Concept Videos

Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
Imaging Studies V: Intravenous Urography and Retrograde Pyelography01:22

Imaging Studies V: Intravenous Urography and Retrograde Pyelography

IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

Imaging Studies I: Kidney, Ureter, and Bladder Studies

Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...