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Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition
Published on: June 21, 2024
Update on imaging for suspected renovascular hypertension in children and adolescents
Stephen D Marks1, Kjell Tullus
1Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK. stephen.marks@gosh.nhs.uk
Insights
Renovascular disease is a key consideration in children with high blood pressure, even with obesity. Early detection through advanced imaging can lead to effective treatment for these young patients.
Area of Science:
- Pediatric Nephrology
- Cardiovascular Research
- Medical Imaging
Background:
- Childhood obesity is increasing primary hypertension in developed nations.
- Renovascular disease is a critical, yet often overlooked, cause of hypertension in children.
- Identifying renovascular disease offers a treatable pathway for pediatric hypertension.
Purpose of the Study:
- To investigate the prevalence and diagnostic approaches for renovascular disease in pediatric hypertension.
- To highlight the importance of considering renovascular disease in children with uncontrolled hypertension.
- To evaluate current imaging modalities for diagnosing renovascular disease.
Main Methods:
- Review of diagnostic imaging techniques including Doppler renal ultrasonography, computed tomography angiography (CTA), and magnetic resonance angiography (MRA).
- Emphasis on digital subtraction angiography as the gold standard for diagnosis.
- Clinical identification criteria such as poor blood pressure control despite multiple medications or associated syndromes.
Main Results:
- Advances in Doppler ultrasonography, CTA, and MRA have improved detection capabilities.
- Digital subtraction angiography remains the definitive diagnostic tool.
- Renovascular disease is a treatable cause of hypertension in pediatric patients.
Conclusions:
- Renovascular disease should be actively investigated in children with difficult-to-control hypertension.
- Digital subtraction angiography is crucial for both diagnosis and potential therapeutic intervention.
- Timely diagnosis and treatment of renovascular disease can significantly improve outcomes in pediatric hypertension.
Abstract:
Although the epidemic of childhood obesity in the developed world has resulted in more children being diagnosed with primary hypertension, renovascular disease remains an important consideration. The reason for investigation is to try and delineate if renovascular disease is present, as there is the potential to treat this group of patients. Those patients are usually identified by poor blood pressure control, despite the use of multiple anti-hypertensive medications or having known associated syndromes. Although advances in Doppler renal ultrasonography, computed tomography angiography (CTA) and magnetic resonance angiography (MRA) have occurred over the last decade, digital subtraction angiography remains the gold standard investigation, and offers a possible therapeutic intervention at the same time.
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