[The computer morphometry of synoviocytes: the diagnostic possibilities and importance for patients with...

The article deals with the data of computer morphometric analysis ofsynovial cells in 27 patients 35-53 years old with knee joint posttraumatic osteoarthritis stage I-II according Kellgren and Lowrence classification. The proposed technique of image computer analysis made it possible to apply a large specter of cardio-metric studies of pathologic processes in synovia of patients with post-traumatic osteoarthritis. The study results favored the implementation in computer morphometry new indicators characterizing brightness and optical density of image and permitting to evaluate the degree of compactization and amount of DNA in cells nuclei. The synoviocytes were differentiated on types I, II and III on basis of form parameters and histograms of distribution of cells nuclei brightness. The results of computer analysis of kinetics of proliferation of these cells dyed by Feulgen testified that in synovia of patients with post-traumatic osteoarthritis synoviocytes type II were in G1 -period of interphase and synoviocytes type III were in S-period or G2 -period of interphase.