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Published on: May 31, 2018
Practical utility and reliability of whole-room calorimetry in young children
Xanne Janssen1, Dylan Cliff, Anthony D Okely
1Interdisciplinary Educational Research Institute, University of Wollongong, Wollongong, NSW 2500, Australia. xj512@uowmail.edu.au
Insights
Whole-room calorimetry (WRC) is feasible in 4- to 6-year-old children, providing valuable insights into children's energy balance. This method allows for reliable resting energy expenditure measurements, even after a small meal.
Area of Science:
- Pediatric Nutrition
- Human Physiology
- Metabolic Research
Background:
- Understanding children's energy balance is crucial for addressing childhood obesity and metabolic disorders.
- Whole-room calorimetry (WRC) offers precise energy expenditure measurements but its application in young children is limited by feasibility concerns.
Purpose of the Study:
- To assess the feasibility and reliability of using whole-room calorimetry (WRC) in children aged 4–6 years.
- To evaluate the impact of diet-induced thermogenesis on resting energy expenditure (REE) measurements in this age group.
Main Methods:
- Forty children (4–6 years) underwent a graded activity protocol within a WRC.
- Six children participated in resting protocols to assess diet-induced thermogenesis and REE reliability.
- Refusal rates and data loss were quantified to determine practical utility.
Main Results:
- Seventy-nine percent of participants provided acceptable data across all activity levels.
- Resting energy expenditure (REE) measurements were similar after a 90-minute fast and an overnight fast (P=0.472).
- Measured REE was significantly higher than predicted Basal Metabolic Rate (BMR) using the Schofield equation (P=0.024–0.042).
Conclusions:
- Whole-room calorimetry (WRC) is a feasible and standardizable method for assessing energy expenditure in 4- to 6-year-old children when using a developmentally sensitive approach.
- A small, standardized breakfast approximately 90 minutes prior to measurement has a minimal impact on REE.
- WRC can provide reliable energy balance data in young children, advancing pediatric metabolic research.
Abstract:
The use of whole-room calorimetry (WRC) in young children can increase our understanding of children's energy balance. However, studies using WRC in young children are rare due to concerns about its feasibility. To assess the feasibility of WRC in young children, forty children, aged 4–6 years, were asked to follow a graded activity protocol while in a WRC. In addition, six children participated in two additional resting protocols to examine the effect of diet-induced thermogenesis on resting energy expenditure (REE) measures and the reliability of REE measurement. Refusals to participate and data loss were quantified as measures of practical utility, and REE measured after an overnight fast and after a 90-min fast were compared. In addition, both were compared to predicted BMR values using the Schofield equation. Our results showed that thirty (78·9 %) participants had acceptable data for all intensities of the activity protocol. The REE values measured after a 90-min fast (5·07 (SD 1·04) MJ/d) and an overnight fast (4·73 (SD 0·61) MJ/d) were not significantly different from each other (P= 0·472). However, both REE after an overnight fast and a 90-min fast were significantly higher than predicted BMR (3·96 (SD 0·18) MJ/d) using the Schofield equation (P= 0·024 and 0·042, respectively). We conclude that, with a developmentally sensitive approach, WRC is feasible and can be standardised adequately even in 4- to 6-year-old children. In addition, the effect of a small standardised breakfast, approximately 90 min before REE measurements, is likely to be small.
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