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Updated: May 18, 2026
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In Vivo Assessment of Rodent Plasmodium Parasitemia and Merozoite Invasion by Flow Cytometry
Published on: April 5, 2015
Quantification of sporozoite invasion, migration, and development by microscopy and flow cytometry
Photini Sinnis1, Patricia De La Vega, Alida Coppi
1Department of Molecular Microbiology and Immunology, John Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. psinnis@jhsph.edu
Methods in Molecular Biology (Clifton, N.J.)
|September 20, 2012
Abstract:
There is an important role for in vitro assays to better understand the initial steps of malaria infection. In this section, we describe both microscopy-based and flow cytometry-based sporozoite invasion, migration and development assays with the rodent malaria parasites, Plasmodium berghei and Plasmodium yoelii, and the human malaria parasite, Plasmodium falciparum.
