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Related Concept Videos

Sperm Structure and Semen Composition01:22

Sperm Structure and Semen Composition

During ejaculation, males release around 2-5 milliliters of semen, which is a complex mixture of mature sperm and various fluids produced by accessory glands. The mature sperm cells measure approximately 60 micrometers in length and consist of a head, neck, midpiece, and tail. The head is flattened and tapered, measuring about 4 to 5 micrometers in length. It contains a nucleus with condensed chromosomes and an acrosome, a cap-like structure filled with enzymes essential for penetrating the...
Spermatogenesis01:41

Spermatogenesis

Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male reproductive...

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Articles linked to this work by shared authors, journal, and citation graph.

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Standards in semen examination: publishing reproducible and reliable data based on high-quality methodology.

Human reproduction (Oxford, England)·2022
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Male reproductive health statement (XIIIth international symposium on Spermatology, may 9th-12th 2018, Stockholm, Sweden.

Basic and clinical andrology·2018
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Evaluation of the relation between preapoptotic sperm rate in ejaculate and intrauterine insemination success rate in patients with unexplained infertility.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology·2016
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Obesity is associated with increased seminal insulin and leptin alongside reduced fertility parameters in a controlled male cohort.

Reproductive biology and endocrinology : RB&E·2014
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Measurement and significance of sperm morphology.

Asian journal of andrology·2010
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Clinical significance of the low normal sperm morphology value as proposed in the fifth edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen.

Asian journal of andrology·2010
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Related Experiment Video

Updated: May 18, 2026

Sperm Collection of Differential Quality Using Density Gradient Centrifugation
03:28

Sperm Collection of Differential Quality Using Density Gradient Centrifugation

Published on: November 29, 2018

Sperm morphology assessment using strict (tygerberg) criteria.

Roelof Menkveld1

  • 1Andrology Laboratory, Department of Obstetrics and Gynaecology, Tygerberg Academic Hospital and University of Stellenbosch, Tygerberg, South Africa. rme@sun.ac.za

Methods in Molecular Biology (Clifton, N.J.)
|September 21, 2012
PubMed
Summary

Sperm morphology evaluation remains crucial for male fertility assessment, despite recent low reference values. Accurate analysis and detailed abnormality reporting are vital for selecting appropriate assisted reproductive techniques (ART).

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Related Experiment Videos

Last Updated: May 18, 2026

Sperm Collection of Differential Quality Using Density Gradient Centrifugation
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Separation of Spermatogenic Cell Types Using STA-PUT Velocity Sedimentation
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Fluorimetric Techniques for the Assessment of Sperm Membranes

Published on: November 28, 2018

Area of Science:

  • Andrology
  • Reproductive Medicine
  • Clinical Laboratory Science

Background:

  • Sperm morphology evaluation is a key component of semen analysis.
  • Recent WHO guidelines (2010) established a low normal reference value (4%) for morphologically normal spermatozoa.
  • This has led some to question the relevance of morphology assessment in clinical practice.

Purpose of the Study:

  • To emphasize the continued importance of accurate sperm morphology evaluation.
  • To highlight the necessity of standardized procedures for reliable results.
  • To underscore the predictive value of morphology data for male fertility and assisted reproductive techniques (ART) selection.

Main Methods:

  • Describes standardized methods for human sperm morphology evaluation.
  • Focuses on performing morphology assessments according to high standards.
  • Details the importance of reporting specific types of abnormalities.

Main Results:

  • Accurate sperm morphology evaluation, when performed correctly, holds high predictive value for male fertility potential.
  • Detailed reporting of abnormality types is crucial for guiding ART decisions.
  • Standardized methods ensure the continued relevance and utility of morphology data.

Conclusions:

  • Sperm morphology assessment remains a critical factor in male fertility evaluation.
  • Adherence to standardized procedures is essential for accurate and relevant results.
  • In-depth reporting of sperm abnormalities aids in selecting optimal ART strategies like IUI, IVF, or ICSI.