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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Heart Valves01:16

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular tachycardia.

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Related Experiment Video

Updated: May 18, 2026

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves
11:12

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves

Published on: October 17, 2013

Symetis ACURATE TA valve.

Jörg Kempfert1, Helge Möllmann, Thomas Walther

  • 1Department of Cardiac Surgery, Kerckhoff Clinic Bad Nauheim, Bad Nauheim, Germany.

Eurointervention : Journal of Europcr in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
|September 22, 2012
PubMed
Summary
This summary is machine-generated.

The ACURATE TA transcatheter aortic valve prosthesis offers a novel transapical solution for aortic stenosis. Its unique implantation technique shows promising results, including a low rate of paravalvular leaks.

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Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves
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Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
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Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement

Published on: January 20, 2022

Area of Science:

  • Cardiovascular Surgery
  • Medical Devices
  • Bioprosthetics

Background:

  • Aortic stenosis is a significant cause of morbidity and mortality.
  • Transcatheter Aortic Valve Implantation (TAVI) has emerged as a less invasive alternative to surgical valve replacement.
  • Transapical access offers an alternative route for TAVI device delivery.

Purpose of the Study:

  • To describe the technical aspects of the ACURATE TA transcatheter aortic valve prosthesis.
  • To detail the specific implantation technique for the ACURATE TA device.
  • To report initial outcomes from pre-approval multicentre trials.

Main Methods:

  • The ACURATE TA prosthesis features a self-expandable nitinol stent with a porcine bioprosthesis.
  • A unique two-step implantation technique is employed for intuitive positioning.
  • Data were collected from two pre-approval multicentre trials.

Main Results:

  • The ACURATE TA device is specifically designed for transapical access.
  • The implantation technique facilitates intuitive device positioning.
  • Promising results were observed, notably a low rate of paravalvular leaks.

Conclusions:

  • The ACURATE TA prosthesis represents a new transapical TAVI device.
  • The device has obtained CE mark and is commercially available in Europe.
  • Further development for transfemoral access is underway.