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Otogenic pneumocephalus as a complication of multiple myeloma
Melissa J Maguire1, Uma Nath, Guiseppe E Bignardi
1Department of Neurology, Leeds General Infirmary, Leeds, England. Maguirem@doctors.org.uk
Abstract:
We report a case of otogenic pneumocephalus in an 80-year-old woman with multiple myeloma. The pneumocephalus was associated with Haemophilus influenzae otitis media and reactive meningitis in the absence of an intracranial brain abscess. Myeloma causes thinning of bone trabeculae and destructive lytic bone lesions. This can predispose to a risk of pathologic fractures and, in patients with skull vault involvement, to the rare complication of pneumocephalus. Therefore, pneumocephalus should be considered in the differential diagnosis of acute headache in patients with multiple myeloma, especially those with skull vault involvement. Prompt computed tomography and liaison between the otolaryngology and neurology teams may assist in making an early diagnosis and preventing life-threatening intracranial complications.
Insights
Otogenic pneumocephalus, or air in the skull from ear infection, is a rare complication in multiple myeloma patients. Early diagnosis via CT scans is crucial for preventing serious intracranial issues.
Area of Science:
- Neurology
- Otolaryngology
- Oncology
Background:
- Multiple myeloma can weaken skull bones, increasing fracture risk.
- Skull involvement in myeloma can lead to rare complications like pneumocephalus.
- Otogenic pneumocephalus is a serious condition requiring prompt medical attention.
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