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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Related Experiment Video

Updated: May 18, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Advanced neuroimaging to guide acute stroke therapy.

Gurpreet Singh Sandhu¹, Jeffrey L Sunshine

¹Department of Radiology, University Hospitals and Case Western Reserve University, Cleveland, OH 44106, USA.

Current Cardiology Reports

|September 25, 2012

Summary

Advanced imaging like CT and MRI angiography can identify acute stroke patients who benefit from reperfusion therapy, especially outside the 3-hour window. These techniques assess vascular lesions and estimate tissue at risk, guiding treatment decisions for better outcomes.

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A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Published on: September 16, 2017

Area of Science:

Neurology
Radiology
Medical Imaging

Background:

Non-contrast CT is the traditional first-line imaging for acute stroke.
It effectively identifies candidates for reperfusion therapy within 3 hours if no hemorrhage is present.
However, non-contrast CT has limitations in selecting optimal candidates outside this narrow time window.

Purpose of the Study:

To evaluate advanced imaging techniques for identifying acute ischemic stroke reperfusion therapy candidates.
To determine the utility of CT and MR angiography in characterizing vascular lesions.
To assess the role of CT and MRI perfusion imaging in estimating ischemic core and penumbra.

Main Methods:

Utilized non-invasive CT angiography and MR angiography for vascular lesion identification.
Employed CT-based perfusion imaging and MRI-based diffusion and perfusion imaging.
Evaluated imaging findings to estimate the extent of fixed core and penumbra in ischemic lesions.

Main Results:

Advanced imaging techniques successfully identify reperfusion therapy candidates beyond the 3-hour window.
CT/MR angiography characterizes vascular lesions like occlusions, aneurysms, and malformations.
Perfusion imaging quantifies ischemic core and penumbra, crucial for treatment selection.

Conclusions:

Advanced imaging, including CT/MR angiography and perfusion techniques, improves selection of acute ischemic stroke patients for reperfusion therapy.
Identifying patients with small infarct cores and large penumbra is key for successful treatment.
These methods enhance therapeutic decision-making, especially for patients presenting outside the early time window.