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Published on: February 10, 2011
Identification of VanN-type vancomycin resistance in an Enterococcus faecium isolate from chicken meat in Japan
Takahiro Nomura1, Koichi Tanimoto, Keigo Shibayama
1Department of Bacteriology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan.
Abstract:
Five VanN-type vancomycin-resistant Enterococcus faecium strains were isolated from a sample of domestic chicken meat in Japan. All isolates showed low-level resistance to vancomycin (MIC, 12 mg/liter) and had the same pulsed-field gel electrophoresis profile. The vancomycin resistance was encoded on a large plasmid (160 kbp) and was expressed constitutively. The VanN-type resistance operon was identical to the first resistance operon to be reported, with the exception of a 1-bp deletion in vanT(N) and a 1-bp substitution in vanS(N).
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