Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Upsampling01:22

Upsampling

Managing signal sampling rates is essential in digital signal processing to maintain signal integrity. A decimated signal, characterized by a reduced frequency range due to its lower sampling rate, can be upsampled by inserting zeros between each sample. This upsampling process expands the original spectrum and introduces repeated spectral replicas at intervals dictated by the new Nyquist frequency. To refine this zero-inserted sequence, it is passed through a lowpass filter with a cutoff...
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Aliasing01:18

Aliasing

Accurate signal sampling and reconstruction are crucial in various signal-processing applications. A time-domain signal's spectrum can be revealed using its Fourier transform. When this signal is sampled at a specific frequency, it results in multiple scaled replicas of the original spectrum in the frequency domain. The spacing of these replicas is determined by the sampling frequency.
If the sampling frequency is below the Nyquist rate, these replicas overlap, preventing the original signal...
X-ray Imaging01:24

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...
Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ultrasound-Based Techniques for Visualization of Dermal Microvasculature: A Scoping Review.

Diagnostics (Basel, Switzerland)·2026
Same author

Human lymph node microvascular imaging using a fast contrast-free super-resolution ultrasound technique.

Scientific reports·2025
Same author

Analysing the Renal Vasculature Using Super-Resolution Ultrasound Imaging: Considerations for Clinical and Research Applications.

Diagnostics (Basel, Switzerland)·2025
Same author

The Zucker Diabetic Fatty Rat as a Model for Vascular Changes in Diabetic Kidney Disease: Characterising Hydronephrosis.

Diagnostics (Basel, Switzerland)·2025
Same author

Real-Time Full-Volume Row-Column Imaging.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control·2025
Same author

Beamformer for a Lensed Row-Column Array in 3-D Ultrasound Imaging.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control·2025

Related Experiment Video

Updated: May 18, 2026

Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform
06:25

Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform

Published on: February 12, 2014

Compounding in synthetic aperture imaging.

Jens Munk Hansen1, Jørgen Arendt Jensen

  • 1Department of Electrical Engineering, Technical University of Denmark, Kgs. Lyngby, Denmark. jmh@elektro.dtu.dk

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
|September 26, 2012
PubMed
Summary

Synthetic aperture compounding enhances ultrasound imaging by creating compound images from multiple angles without sacrificing frame rate. This novel method improves speckle reduction and contrast resolution for better lesion detection.

More Related Videos

Confocal Microscopy Reveals Cell Surface Receptor Aggregation Through Image Correlation Spectroscopy
06:51

Confocal Microscopy Reveals Cell Surface Receptor Aggregation Through Image Correlation Spectroscopy

Published on: August 2, 2018

High-plex Imaging using Spectral Confocal Microscopy to Minimize Non-specific Tissue Fluorescence
10:28

High-plex Imaging using Spectral Confocal Microscopy to Minimize Non-specific Tissue Fluorescence

Published on: October 28, 2025

Related Experiment Videos

Last Updated: May 18, 2026

Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform
06:25

Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform

Published on: February 12, 2014

Confocal Microscopy Reveals Cell Surface Receptor Aggregation Through Image Correlation Spectroscopy
06:51

Confocal Microscopy Reveals Cell Surface Receptor Aggregation Through Image Correlation Spectroscopy

Published on: August 2, 2018

High-plex Imaging using Spectral Confocal Microscopy to Minimize Non-specific Tissue Fluorescence
10:28

High-plex Imaging using Spectral Confocal Microscopy to Minimize Non-specific Tissue Fluorescence

Published on: October 28, 2025

Area of Science:

  • Medical Imaging
  • Ultrasound Technology
  • Signal Processing

Background:

  • Spatial compounding in ultrasound improves image quality by reducing speckle and enhancing contrast resolution.
  • Conventional spatial compounding methods often compromise frame rate and temporal resolution.
  • Synthetic aperture imaging offers a flexible platform for advanced ultrasound techniques.

Purpose of the Study:

  • To investigate a novel method for spatial compounding using synthetic aperture data with a convex array transducer.
  • To evaluate the impact of synthetic aperture compounding on frame rate, temporal resolution, speckle reduction, and contrast resolution.
  • To optimize synthetic aperture size for lesion detection based on speckle information density.

Main Methods:

  • Exploiting the linearity of delay-and-sum beamformation to synthesize multiple transmit and receive apertures from multiple spherical emissions.
  • Incoherently adding multiple images acquired from different angles to form a single compound image.
  • Utilizing a 192-element, 3.5-MHz, λ-pitch transducer for tissue-phantom and wire-phantom measurements.

Main Results:

  • Synthetic aperture compounding allows spatial compounding at any angle without reducing frame rate or temporal resolution.
  • Tissue-phantom measurements demonstrated significant speckle reduction and improved contrast resolution.
  • Speckle information density improved by 25% compared to dynamic receive focusing compounding.
  • Cystic resolution improved by 41% compared to conventional imaging when using the full aperture for synthetic aperture compounding.

Conclusions:

  • Synthetic aperture compounding is an effective technique for improving ultrasound image quality, particularly speckle reduction and contrast resolution.
  • This method overcomes limitations of conventional spatial compounding by maintaining high frame rates and temporal resolution.
  • Optimized synthetic aperture compounding shows significant potential for enhanced lesion detection and diagnostic accuracy in medical ultrasound.