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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Endovascular therapy in children with acute ischemic stroke: review and recommendations

Michael J Ellis1, Catherine Amlie-Lefond, Darren B Orbach

  • 1Division of Neurosurgery, The Hospital for Sick Children, University of Toronto, Toronto, Canada.

Neurology
|September 26, 2012
PubMed

Insights

Interventional management for acute ischemic stroke in children is under-researched, with limited case studies available. Future research should focus on pediatric-specific endovascular stroke therapies and clinical trials.

Area of Science:

  • Pediatric Neurology
  • Interventional Neuroradiology
  • Vascular Neurology

Background:

  • Limited data exists on interventional management of acute ischemic stroke in children.
  • Current systemic or local thrombolysis trials exclude pediatric patients.
  • Mechanical thrombectomy trials using clot retrievers exclude patients under 18.

Purpose of the Study:

  • To summarize available data on interventional acute ischemic stroke management in children.
  • To discuss the potential future of endovascular stroke therapy in pediatric populations.
  • To provide author-based recommendations derived from limited literature.

Main Methods:

  • Review of existing case series on interventional acute ischemic stroke therapy in children.
  • Analysis of the current literature regarding endovascular stroke treatments for pediatric patients.
  • Synthesis of expert opinion based on limited available evidence.

Main Results:

  • The literature on interventional stroke therapy for children is scarce.
  • Prospective trials specifically for pediatric acute ischemic stroke are lacking.
  • Existing major thrombolysis and thrombectomy trials have excluded children.

Conclusions:

  • There is a critical need for prospective trials in pediatric acute ischemic stroke.
  • Current recommendations for interventional stroke therapy in children are based on limited case series.
  • Further research into endovascular approaches for pediatric stroke is warranted.

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