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Arthur S Yang¹, Terrence A Creagh

¹Department of Plastic and Reconstructive Surgery, Christchurch Hospital, Riccarton Avenue, Private Bag 4710, Christchurch 8140, New Zealand. ayang.nz@gmail.com

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Summary

Cutaneous tattoos can mimic melanoma spread, leading to false-positive sentinel lymph node biopsy results. Routine tattoo history is crucial for accurate melanoma staging and treatment decisions.

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Dissection and 2-Photon Imaging of Peripheral Lymph Nodes in Mice

Dissection and 2-Photon Imaging of Peripheral Lymph Nodes in Mice

Published on: August 23, 2007

Area of Science:

Oncology
Dermatology
Surgical Pathology

Background:

Sentinel lymph node biopsy (SLN) is a critical staging procedure for primary cutaneous melanoma.
Accurate SLN identification relies on radiotracer and dye visualization.
Cutaneous tattoos are increasingly common and may interfere with SLN assessment.

Observation:

A young adult with cutaneous melanoma presented with two radio-nucleotide tracer-active sentinel lymph nodes.
These nodes were black-stained, consistent with the patient's tattoos.
Histopathology confirmed the tracer activity was due to tattoo pigment, not melanoma metastasis.

Findings:

The presence of tattoo pigment in SLNs can lead to false positives.
This finding averted the need for a potentially unnecessary elective regional node dissection.
The case highlights a potential diagnostic pitfall in melanoma staging.

Implications:

Obtaining a detailed history of tattooing and tattoo removal is essential for all melanoma patients undergoing SLN biopsy.
Proper staging of SLN biopsy and completion node dissection is vital for accurate diagnosis and treatment planning.
This emphasizes the importance of integrating patient history with imaging and pathology for optimal oncologic care.