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Published on: November 6, 2019
Antibiotics do not reduce post-tonsillectomy morbidity in children
Abdulmonem Al-Layla1, Tareq M Mahafza
1ENT Department, Jordan University Hospital, Faculty of Medicine, University of Jordan, PO Box 13046, Amman, Jordan.
Insights
Antibiotic use after tonsillectomy in children did not reduce complications like fever or pain. Routine antibiotic prescription is not recommended; consider it only on a case-by-case basis for post-tonsillectomy care.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Infectious Diseases
Background:
- Post-tonsillectomy morbidity, including fever, pain, and bleeding, can impact pediatric recovery.
- The routine use of antibiotics to mitigate these complications is a common practice but lacks robust evidence.
Purpose of the Study:
- To evaluate the effectiveness of antibiotic administration in reducing common morbidities following tonsillectomy in children.
Main Methods:
- A randomized clinical trial was conducted with pediatric patients undergoing tonsillectomy.
- Patients were divided into two groups: one received amoxicillin with clavulanic acid post-operatively, while the control group received no antibiotics.
- Outcomes measured included fever, secondary bleeding, throat pain duration, and time to resume a normal diet.
Main Results:
- Secondary bleeding occurred more frequently in the antibiotic group (5.5%) compared to the no-antibiotic group (2%).
- Average throat pain duration and time to resume a normal diet were slightly longer in the antibiotic group.
- Fever rates were similar between the two groups (31% vs. 30%).
Conclusions:
- Post-tonsillectomy antibiotic use does not appear to decrease post-operative morbidity in children.
- Routine antibiotic prescription following tonsillectomy is not supported; individualized assessment is advised.
Abstract:
The objectives are to assess the efficacy of antibiotics in reducing post-tonsillectomy morbidities in children. This is a clinical trial study that was undertaken at the Jordan University Hospital during the period from June 2008 to July 2009. All patients undergoing tonsillectomy were randomly divided into two matched groups on alternating basis: group A included patients who received antibiotics (amoxicillin with clavulanic acid) for 5 days in the post-tonsillectomy period and group B included patients who received none. The two groups were compared with respect to fever, secondary bleeding, throat pain, and the time to resume to normal diet. Bleeding was more common in group A (5.5 %) than in group B (2 %). The average duration of throat pain was 4.2 days in group A, while it was 3.9 days in group B. The average time to resume normal diet was 5.7 days in group A, whereas it was 5.3 days in group B. Fever was noted in 17 (31 %) patients from group A, while it was observed in 15 (30 %) patients from group B. The use of antibiotics in the post-tonsillectomy period does not reduce post-operative morbidity in children and therefore it is advised to use antibiotics on an individual basis rather than routinely for patients undergoing tonsillectomy.
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