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Published on: July 5, 2021
Post-embolisation susceptibility changes in giant meningiomas: multiparametric histogram analysis using
Tomokazu Nishiguchi1, Takeshi Iwakiri, Kohji Hayasaki
1Department of Radiology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno, Osaka 545-8585, Japan. tomokazu-n@med.osaka-cu.ac.jp
Purpose:
To investigate imaging characteristics of post-embolised meningioma and to determine if SW imaging can delineate tumour ischaemia.
Materials And Methods:
Sixteen patients were studied before and after preoperative embolisation therapy (8 histopathologically determined with ischaemia, 8 with non-ischaemia). In each patient, a slice-wise ROI for the entire tumour was established, and histogram variables (mean, SD, minimum, maximum, histogram width, mode, and peak height) of SW, ADC, CBV, CBF, MTT, and TTP maps were compared between ischaemic and non-ischaemic groups. Changes in SW histogram were correlated with histopathological characteristics.
Results:
Signal intensity on the SW map tended to decrease in the ischaemic group and partially increased in the non-ischaemic group. A similar trend was observed on the ADC map. The PW histogram showed an MTT increase in ischaemic group; however, CBV did not show significant changes between ischaemic and non-ischaemic groups. Microhaemorrhage was slightly correlated with Δpeak height in the SW histogram.
Conclusion:
Post-embolisation changes of intrinsic T2-weighted MR contrasts on SW map are most likely associated with alterations in deoxyhaemoglobin levels and arterial blood flow.
