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Synovial sarcoma involving the median nerve: a case report
Anna Lisa Tosi1, Giulio Fraternali Orcioni, Dario de Biase
1University of Bologna, Bellaria Hospital, Section of Anatomic Pathology "M. Malpighi", Bologna, Italy. annalisa.tosi3@unibo.it
Turk Patoloji Dergisi
|September 27, 2012
Summary
This case report details a rare biphasic synovial sarcoma invading the radial nerve. The tumor, found in a 59-year-old female, showed the characteristic chromosomal translocation (X;18).
Area of Science:
- Oncology
- Orthopedic Surgery
- Genetics
Background:
- Synovial sarcoma is a rare soft tissue sarcoma.
- It typically affects the extremities but can arise in unusual locations.
- Genetic analysis, specifically chromosomal translocation (X;18), is key for diagnosis.
Observation:
- A case of biphasic synovial sarcoma invading the radial nerve is presented.
- The patient was a 59-year-old female.
- The tumor exhibited the classic t(X;18) chromosomal translocation.
Findings:
- Biphasic synovial sarcoma can occur in unusual anatomical sites, such as the radial nerve.
- The chromosomal translocation (X;18) is a hallmark diagnostic feature.
- Differential diagnosis from other nerve sheath tumors and sarcomas is crucial.
Implications:
- Highlights the importance of considering rare tumor presentations in clinical practice.
- Emphasizes the role of cytogenetics in diagnosing synovial sarcoma.
- Informs surgical and oncological management strategies for rare synovial sarcoma presentations.
