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Interrelationship of variable coupling, multiformity and repetitive forms: implications for classification of
M Lowery1, E J de Marchena, A Castellanos
1Department of Medicine, University of Miami School of Medicine, FL 33125.
American Heart Journal
|February 1, 1990
Summary
Variable coupling and multiformity of premature ventricular complexes (PVCs) are strongly linked to repetitive PVC forms. Most patients with these characteristics exhibited repetitive PVCs, indicating a significant association.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Premature ventricular complexes (PVCs) are common arrhythmias.
- Understanding the predictors of repetitive PVCs is crucial for risk stratification.
Purpose of the Study:
- To investigate the relationship between variable coupling, multiformity of single PVCs, and the occurrence of repetitive PVC forms.
Main Methods:
- Prospective analysis of 100 24-hour ambulatory electrocardiograms.
- Categorization of PVCs using a three-tier decision tree based on multiformity, variable coupling (>80 msec), and repetitive forms (≥2 consecutive PVCs).
Main Results:
- Variable coupling was present in 51 patients, with 69% showing repetitive forms.
- Multiformity was observed in 46 patients, with 80% exhibiting repetitive forms.
- Multiformity and variable coupling were significantly associated with repetitive PVCs (p < 0.005).
Conclusions:
- Variable coupling and multiformity are significant predictors of repetitive premature ventricular complexes.
- Patients with multiformity and variable coupling demonstrate a substantially higher incidence of repetitive PVCs compared to those with uniform, fixed-coupled PVCs.