Fever, irritability, and ulcerations in an infant

Related Experiment Video

Updated: May 18, 2026

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
08:50

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development

Published on: June 24, 2020

Devika Patel1, Nathan Cook, Brandon Newell

  • 1University of Missouri, Kansas City, MissouriUniversity of North Carolina, Wilmington, North CarolinaChildren's Mercy Hospital and Clinics, Kansas City, Missouri.

Pediatric Dermatology
|September 28, 2012
PubMed

Insights

Neonatal Behçet

Area of Science:

  • Pediatric rheumatology and immunology
  • Neonatal medicine

Background:

  • Neonatal Behçet's disease is a rare condition presenting with systemic inflammation in infants.
  • Early diagnosis and treatment are crucial for preventing long-term complications.

Observation:

  • A young infant presented with fever and painful oral ulcerations.
  • Comprehensive workup excluded infectious, nutritional, and immunodeficiency causes.

Findings:

  • Maternal history raised suspicion for neonatal Behçet's disease.
  • Treatment specific to Behçet's disease led to rapid and sustained clinical improvement.

Implications:

  • This case highlights the importance of considering neonatal Behçet's disease in infants with unexplained fever and oral lesions.
  • Prompt diagnosis and management can significantly improve outcomes for affected neonates.

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