Related Experiment Video
Updated: May 18, 2026
Infant Auditory Processing and Event-related Brain Oscillations
Published on: July 1, 2015
Automating the analysis of EEG recordings from prematurely-born infants: a Bayesian approach
Timothy J Mitchell1, Jeffrey J Neil, John M Zempel
1Department of Pediatrics, Washington University, St. Louis, MO 63110, USA. mitchell@physics.wustl.edu
Objective:
To implement an automated analysis of EEG recordings from prematurely-born infants and thus provide objective, reproducible results.
Methods:
Bayesian probability theory is employed to compute the posterior probability for developmental features of interest in EEG recordings. Currently, these features include smooth delta waves (0.5-1.5Hz, >100μV), delta brushes (delta portion: 0.5-1.5Hz, >100μV; "brush" portion: 8-22Hz, <75μV), and interburst intervals (<10μV), though the approach taken can be generalized to identify other EEG features of interest.
Results:
When compared with experienced electroencephalographers, the algorithm had a true positive rate between 72% and 79% for the identification of delta waves (smooth or "brush") and interburst intervals, which is comparable to the inter-rater reliability. When distinguishing between smooth delta waves and delta brushes, the algorithm's true positive rate was between 53% and 88%, which is slightly less than the inter-rater reliability.
Conclusion:
Bayesian probability theory can be employed to consistently identify features of EEG recordings from premature infants.
Significance:
The identification of features in EEG recordings provides a first step towards the automated analysis of EEG recordings from premature infants.
