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Late developing lesions in birdshot retinochoroidopathy.
G Soubrane1, R Bokobza, G Coscas
1Eye University Clinic of Creteil, University of Paris-XII, France.
American Journal of Ophthalmology
|February 15, 1990
Summary
Birdshot retinochoroidopathy, a condition causing optic disc spots, can develop years after initial uveitis symptoms. Early HLA-A29 antigen testing is recommended for long-standing retinal inflammation.
Area of Science:
- Ophthalmology
- Immunology
Background:
- Birdshot retinochoroidopathy presents with optic disc depigmented spots, vitritis, retinal vasculitis, and optic nerve head involvement.
- The condition is strongly associated with the HLA-A29 antigen.
Observation:
- Two patients with uveitis, vitritis, retinal vasculitis, and papillitis developed characteristic birdshot retinochoroidopathy lesions after 7-8 years.
- This indicates a delayed onset of typical lesions in some cases.
Findings:
- Long-standing inflammation of the retinal vasculature and uveal tract can precede the development of classic birdshot retinochoroidopathy.
- The typical clinical presentation may not manifest until years after initial inflammatory signs.
Implications:
- Assessment of the HLA-A29 antigen is crucial in cases of persistent uveitis with retinal vasculitis and papillitis.
- Delayed diagnosis of birdshot retinochoroidopathy is possible, necessitating long-term monitoring and antigen testing.