Related Experiment Video
Updated: May 18, 2026

08:04
A Mouse Model of Vascularized Heterotopic Spleen Transplantation for Studying Spleen Cell Biology and Transplant Immunity
Published on: June 11, 2019
Adoptive transfer of splenocytes to immunocompromised mice
Brian M Gray1, Kathryn A Eaton
1Unit for Laboratory Animal Medicine, Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA.
Methods in Molecular Biology (Clifton, N.J.)
|September 28, 2012
Abstract:
Analysis of the immune response of mice to Helicobacter infection has been greatly aided by the use of various deficient mouse strains. Here we present protocols for reconstitution of immune-deficient mice with wild-type immune cells and protocols for analysis of the outcome.

