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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Spondylodiscitis in infancy: a potentially fatal condition that can lead to major spinal complications
1Scottish National Spine Deformity Centre, Royal Hospital for Sick Children, Sciennes Road, Edinburgh EH9 1LF, UK. atsirikos@hotmail.com
Insights
Severe infant spondylodiscitis, following pneumonia and septicaemia, can lead to spinal destruction. Early diagnosis and treatment are crucial to prevent severe complications and ensure recovery.
Area of Science:
- Pediatric Infectious Diseases
- Pediatric Orthopedic Surgery
- Pediatric Critical Care Medicine
Background:
- Spondylodiscitis is a serious spinal infection that can affect infants.
- Pneumonia and septicaemia are potential preceding conditions.
- Delayed diagnosis can lead to severe spinal complications.
Observation:
- An infant presented with severe thoracic spondylodiscitis following pneumonia and septicaemia.
- Diagnosis was delayed, resulting in T4-T5 vertebral body destruction and a large abscess.
- The patient underwent multiple surgical interventions, including posterior and anterior spinal fusions.
Findings:
- Antibiotic treatment and abscess aspiration controlled the infection.
- Surgical stabilization prevented progressive kyphosis and achieved bony fusion by age five.
- The patient experienced a favorable outcome with no symptoms at follow-up.
Implications:
- Spondylodiscitis should be considered in the differential diagnosis of critically ill infants with atypical symptoms.
- Prompt diagnosis and management are essential to avoid devastating spinal sequelae.
- Multidisciplinary care involving infectious disease, orthopedic surgery, and critical care is vital for optimal outcomes.
Abstract:
An eight-week-old boy developed severe thoracic spondylodiscitis following pneumonia and septicaemia. A delay in diagnosis resulted in complete destruction of the T4 and T5 vertebral bodies and adjacent discs, with a paraspinal abscess extending into the mediastinum and epidural space. Antibiotic treatment controlled the infection and the abscess was aspirated. At the age of six months, he underwent posterior spinal fusion in situ to stabilise the spine and prevent progressive kyphosis. At the age of 13 months, repeat imaging showed lack of anterior vertebral body re-growth and he underwent anterior spinal fusion from T3 to T6 and augmentation of the posterior fusion. At the age of five years, he had no symptoms and radiographs showed bony fusion across the affected levels. Spondylodiscitis should be included in the differential diagnosis of infants who present with severe illness and atypical symptoms. Delayed diagnosis can result in major spinal complications with a potentially fatal outcome.
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