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Published on: July 22, 2011
Variable expression of O:61 in Salmonella group C2
M Mikoleit1, M S Van Duyne, J Halpin
1Centers for Disease Control and Prevention, National Center for Emerging, Zoonotic, and Infectious Diseases, Division of Foodborne, Waterborne, and Enteric Diseases, Enteric Diseases Laboratory Branch, Atlanta, Georgia, USA. MMikoleit@cdc.gov
The Kauffmann-White scheme classifies Salmonella serogroup C2 pairs based on minor antigen O:6(1). Characterization revealed variable O:6(1) expression, indicating these pairs are not distinct Salmonella serovars.
Area of Science:
- Microbiology
- Bacteriology
- Immunology
Background:
- The Kauffmann-White scheme is a standard for Salmonella serotyping.
- Salmonella serogroup C2 contains 39 pairs of serovars differentiated by the O:6(1) antigen.
Purpose of the Study:
- To investigate the distinctness of Salmonella serogroup C2 serovar pairs.
- To determine if the O:6(1) antigen expression is consistent within these serovar pairs.
Main Methods:
- Bacterial strain characterization.
- Analysis of O:6(1) antigen expression in Salmonella serogroup C2 strains.
Main Results:
- Ten serovars from five Salmonella serogroup C2 pairs were analyzed.
- Variable expression of the O:6(1) antigen was observed across all tested strains.
Conclusions:
- The variable O:6(1) antigen expression challenges the current classification of these Salmonella serogroup C2 pairs.
- These findings suggest that the analyzed pairs may not represent distinct serovars.
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