Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Structure and Function of Platelets01:18

Structure and Function of Platelets

The cell fragments known as platelets are disc-shaped, with an average diameter of about 3 μm and a thickness of roughly 1 μm. They play a crucial role in the body's vascular clotting system, which also involves plasma proteins, blood cells, and blood vessel tissues.
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000 platelets, with...
Formation of the Platelet Plug01:22

Formation of the Platelet Plug

The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cocreating a Responsive Organization: Disclosure and Responsivity in Veterinary Ophthalmology.

Veterinary ophthalmology·2025
Same author

Allyship Into Action.

Veterinary ophthalmology·2025
Same author

Adverse Childhood Experiences, Psychological Distress, and Resilience in Health Professions Students.

Academic medicine : journal of the Association of American Medical Colleges·2025
Same author

Evaluation of clopidogrel response in healthy cats using a novel viscoelastic test and thromboelastography.

Frontiers in veterinary science·2024
Same author

Preliminary evaluation of reference intervals for a point-of-care viscoelastic coagulation monitor (VCM Vet) in healthy adult horses.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2023
Same author

Can veterinary medicine improve diversity in post-graduate training programs? Current state of academic veterinary medicine and recommendations on best practices.

Journal of the American Veterinary Medical Association·2022

Related Experiment Video

Updated: May 18, 2026

Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

Assessment of platelet function.

Karl E Jandrey1

  • 1Department of Surgical and Radiological Sciences, University of California- Davis, School of Veterinary Medicine, Davis, CA 95616, USA. kejandrey@ucdavis.edu

Journal of Veterinary Emergency and Critical Care (San Antonio, Tex. : 2001)
|September 29, 2012
PubMed
Summary

Primary hemostatic disorders are increasingly recognized in veterinary medicine. Point-of-care platelet function (PF) tests offer rapid diagnosis for platelet dysfunction, aiding treatment strategies.

More Related Videos

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor
06:32

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor

Published on: May 2, 2025

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
09:38

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

Related Experiment Videos

Last Updated: May 18, 2026

Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor
06:32

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor

Published on: May 2, 2025

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
09:38

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

Area of Science:

  • Veterinary Internal Medicine
  • Hemostasis and Thrombosis Research
  • Comparative Pathology

Background:

  • Primary hemostasis disorders are common in human medicine, involving platelet function (PF) defects, granule issues, and medication effects.
  • Understanding PF disorders is crucial for diagnosing, monitoring, and treating related conditions in both humans and animals.

Purpose of the Study:

  • To review current in vivo and in vitro platelet function (PF) tests applicable to companion animals.
  • To highlight the growing recognition and diagnostic approaches for primary hemostatic disorders in veterinary patients.

Main Methods:

  • Comprehensive review of scientific literature, including reviews, case reports, original research, and conference proceedings.
  • Analysis of both in vivo and in vitro diagnostic modalities for platelet function.

Main Results:

  • Primary hemostatic disorders are increasingly identified in clinical veterinary practice.
  • Point-of-care analyzers provide rapid diagnosis of platelet dysfunction using small blood volumes.
  • Recent research enhances understanding of PF disorder pathophysiology and potential new treatments.

Conclusions:

  • Assessment of platelet function (PF) can be achieved through point-of-care techniques and specialized laboratory testing.
  • Clinicians must understand the benefits of each testing modality for effective diagnosis of coagulopathies.
  • Ongoing research promises improved understanding and novel therapeutic strategies for PF disorders in companion animals.