Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Antimicrobial Effectiveness

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...

Colloidal precipitates

Colloidal precipitates

The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...

Clinical Significance of Antibiotic Resistance

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...

Antimicrobial Proteins

Antimicrobial Proteins

Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...

Formation of Complex Ions

Formation of Complex Ions

A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...

Surface Membrane Barriers

Surface Membrane Barriers

The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Divergence in poxvirus-encoded E3-like proteins can dictate poxvirus activation of cellular necroptosis.

Journal of virology·2026

Same author

Enrollment Assister Perspectives of a Private Health Insurance Program for Undocumented Immigrants.

JAMA health forum·2026

Same author

AI in science recruitment: friend or foe? Join our free webinar.

Nature·2026

Same author

Science fiction: nine lab-life novels for your holiday reading.

Nature·2026

Same author

Small RNA sequencing datasets from caryopses and flag leaves of multiple rice genotypes exposed to high nighttime temperature stress.

Data in brief·2026

Same author

Portable Detection of Monkeypox virus Clades using Bridging LAMP.

Research square·2026

Search research articles

Related Experiment Video

Updated: May 18, 2026

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Published on: April 21, 2023

Spectrum of antimicrobial activity associated with ionic colloidal silver.

Kira Morrill¹, Kathleen May, Daniel Leek

¹Department of Naturopathic Research, Southwest College of Naturopathic Medicine, Tempe, AZ, USA.

Journal of Alternative and Complementary Medicine (New York, N.Y.)

|September 29, 2012

Summary

This summary is machine-generated.

Ionic colloidal silver effectively inhibits aerobic and anaerobic bacteria growth, though multiple applications may be needed. Its antifungal effects vary by genus, and it shows no efficacy against tested viruses.

More Related Videos

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Published on: April 18, 2019

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

Related Experiment Videos

Last Updated: May 18, 2026

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Published on: April 21, 2023

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Published on: April 18, 2019

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

Area of Science:

Microbiology
Antimicrobial Agents

Background:

Silver has a long history of use as a broad-spectrum antimicrobial agent.
The U.S. Food and Drug Administration (FDA) currently does not recognize colloidal silver as safe or effective.
There is a need for further evaluation of colloidal silver's antimicrobial properties.

Purpose of the Study:

To evaluate the antimicrobial efficacy of ionic colloidal silver.
To assess its effectiveness against various bacterial, fungal, and viral strains.

Main Methods:

Bacterial, fungal, and viral strains were cultured under multicycle growth conditions.
Cultures were exposed to ionic colloidal silver or a control.
Antimicrobial activity was assessed by observing growth inhibition.

Main Results:

Significant growth inhibition of aerobic and anaerobic bacteria was observed, often requiring multiple treatments.
The efficacy of ionic colloidal silver against fungal genera varied considerably.
No inhibition of viral growth was detected across any tested strains.

Conclusions:

Ionic colloidal silver demonstrates broad-spectrum antimicrobial activity against both aerobic and anaerobic bacteria.
Its activity against fungi is more limited and genus-specific.
The compound was ineffective against the tested viruses.