Related Experiment Video
Updated: May 18, 2026

Visual Evoked Potential Recording in a Rat Model of Experimental Optic Nerve Demyelination
Published on: July 29, 2015
Visual evoked potentials in early diagnosis of demyelinating diseases--a case report of Devic's disease
Ewa Langwińska-Wośko1, Kamil Szulborski, Karina Broniek-Kowalik
1Department of Ophthalmology, Warsaw Medical University, Warsaw, Poland.
Background:
Devic's disease, also known as neuromyelinitis optica (NMO), is a severe, rare demyelinating disorder, previously considered to be a form of multiple sclerosis (MS). The aim of this study was to present the case report of 21-year-old woman with a very early diagnosis of Devic's disease, established following electrophysiological testing.
Case Report:
A 21-year-old woman was referred to Warsaw Medical University, Department of Ophthalmology, with subjective visual impairment. The patient underwent a full clinical examination, colour vision and Goldmann visual field testing, fluorescein angiography, OCT, multifocal ERG, and visual evoked potentials (VEPs).
Conclusions:
Visual evoked potentials are a very useful diagnostic tool in optic nerve neuropathies. In our patient, the electrophysiological testing allowed us to establish a proper diagnosis very early, before typical clinical signs of Devic's disease.

