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Updated: May 18, 2026
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Visualizing Lignification Dynamics in Plants with Click Chemistry: Dual Labeling is BLISS!
Published on: January 26, 2018
[Lignans from Sinocalamus affinis].
Mei Zhu1, Liang Xiong, Yanan Wang
1Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Summary
This study isolated fifteen compounds from Sinocalamus affinis stems, including a new natural product. These findings represent the first isolation of these compounds from the Sinocalamus genus.
Area of Science:
- Phytochemistry
- Natural Product Chemistry
- Organic Chemistry
Context:
- Sinocalamus affinis is a species of bamboo with potential medicinal properties.
- Natural products chemistry focuses on the isolation and characterization of bioactive compounds from natural sources.
- Chromatographic techniques are essential for separating complex mixtures of plant-derived compounds.
Purpose:
- To isolate and identify chemical constituents from the stem of Sinocalamus affinis.
- To characterize the structures of isolated compounds using spectroscopic methods.
- To report novel compounds and the first-time isolation of known compounds from this genus.
Summary:
- Fifteen compounds were isolated from Sinocalamus affinis stem using silica gel, macroporous adsorbent resin, Sephadex LH-20, and preparative HPLC.
- Structures were elucidated via spectroscopic data, identifying lignans, a new pyranone derivative (2,6-dimethoxypyran-4-one), beta-sitosterol, 4-hydroxycinnamic acid, and 2,6-dimethoxy-p-benzoquinone.
- Compound 10 (secoisolariciresinol-9,9'-acetonide) is suggested to be an artifact, and all other compounds are reported for the first time from the Sinocalamus genus.
Impact:
- Expands the known chemical diversity of the Sinocalamus genus.
- Provides a foundation for further research into the potential bioactivities and applications of these compounds.
- Contributes to the field of natural product discovery and characterization.
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