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Updated: May 18, 2026
Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
[Study on phenolic constituents of Amomum villosum]
Cheng Chen1, Chen Fu, Wen-Cai Ye
1Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China. cecichen208@sina.com
Objective:
To study the chemical constituents of Amomum villosum.
Methods:
Compounds were isolated from the alcoholic extract using polyamide, silica gel, Sephadex LH-20, ODS open column chromatography and other means. Their structures were elucidated according to spectral data and physiochemical properties.
Results:
Five compounds were isolated from Amomum villosum. They were identified as: 3-ethoxy-hydroxy benzoic acid (1), vanillic acid-1-beta-D-glucopyranosyl ester (2), isorhamnetin-3-beta-D-glucoside (3), flavanocoumarin (4), isoflavanocoumarin (5).
Conclusion:
Compounds 1-5 are isolated from this plant for the first time.
