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Published on: February 3, 2023
[The quality standard study on Hugan qingzhi tablets]
Ben-Jie Zhou1, Yu-Miao Yan, Shu-Xian Huang
1Department of Pharmacy, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. zhoubj163@163.com
A new quality control method for Hugan qingzhi tablets was developed using Thin Layer Chromatography (TLC) and High-Performance Liquid Chromatography (HPLC). This reliable and accurate method ensures the quality of Hugan qingzhi tablets.
Area of Science:
- Pharmacognosy
- Analytical Chemistry
Context:
- Hugan qingzhi tablets are a traditional Chinese medicine.
- Quality control is essential for ensuring the safety and efficacy of herbal medicines.
Purpose:
- To develop and validate a quality control method for Hugan qingzhi tablets.
- To identify key marker compounds and quantify their levels.
Summary:
- Thin Layer Chromatography (TLC) was used to identify Fructus Crataegi, Rhizoma Alismatis, and Radix Notoginseng.
- High-Performance Liquid Chromatography (HPLC) was employed to determine the content of ursolic acid.
- The developed method demonstrated good linearity (r=1.000), high average recovery (99.05%), and low relative standard deviation (1.3%).
Impact:
- Establishes a reliable, accurate, and specific method for Hugan qingzhi tablet quality control.
- Ensures consistent product quality and supports the standardization of traditional Chinese medicine.
- Facilitates regulatory compliance and enhances consumer confidence in Hugan qingzhi tablets.
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