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Updated: May 18, 2026

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Published on: January 17, 2018
Ectopic pyriform sinus parathyroid adenoma
N Guevara1, B Agopian, D Benisvy
1Institut universitaire de la face et du cou, groupement de coopération Sanitaire, centre hospitalier universitaire de Nice, centre Antoine-Lacassagne,31, avenue de Valombrose, 06107 Nice cedex 2, France. guevara.n@chu-nice.fr
Objective:
To describe the diagnosis and treatment of ectopic pyriform sinus parathyroid adenoma.
Material And Methods:
A 44-year-old woman presented with persistent primary hyperparathyroidism after previous failed cervical exploratory surgery.
Results:
Diagnosis of ectopic pyriform sinus parathyroid adenoma was suggested by computed tomography and technetium-99m sestamibi scintigraphy (99mTc-MIBI SPECT/CT). A submucosal tumor was identified under laryngoscopy and resected by endoscopic CO2 laser. Histopathology confirmed the diagnosis of parathyroid adenoma.
Conclusions:
Ectopic pyriform sinus locations are rare in parathyroid adenoma. 99mTc-MIBI SPECT/CT facilitates diagnosis, especially in case of previous failed neck exploration. Endoscopic CO2 laser resection is the treatment of choice.
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