Related Experiment Video
Updated: Aug 20, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Drug-induced sleep endoscopy in the identification of obstruction sites causing obstructive sleep apnea-hypopnea
M Demoures-Patris de Breuil1, F Chatelet2, N Leboulanger3
1Service d'Otorhinolaryngologie Pédiatrique, AP-HP, Hôpital Necker-Enfants Malades, 75015 Paris, France.
Insights
Drug-induced sleep endoscopy (DISE) identified more airway obstruction sites than clinical exams in children with obstructive sleep apnea (OSA). This led to significant changes in surgical plans and improved outcomes.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Surgical Planning
Background:
- Limited evidence compares drug-induced sleep endoscopy (DISE) with clinical examination for guiding multilevel surgery in pediatric obstructive sleep apnea (OSA).
- Accurate identification of obstruction sites is crucial for effective surgical intervention in children with OSA.
Purpose of the Study:
- To evaluate the surgical contribution of DISE compared to traditional clinical examination in pediatric OSA patients.
- To determine if DISE alters surgical strategy and improves outcomes compared to clinical assessment alone.
Main Methods:
- Retrospective cohort study of 240 children with OSA undergoing DISE.
- Comparison of pre-operative clinical examination findings with intraoperative anatomic data from DISE.
- Analysis of surgical strategy changes and post-operative apnea-hypopnea index (AHI) improvement.
Main Results:
- DISE prompted surgical strategy changes in 75% of cases, increasing planned procedures from 597 to 803.
- Agreement between DISE and clinical exam was moderate to weak for most sites, especially tongue base and laryngeal vestibule.
- DISE revealed a significantly higher total anatomic obstruction score and led to significant AHI improvement post-surgery.
Conclusions:
- DISE is superior to clinical examination in identifying multiple obstruction sites in children with OSA.
- DISE significantly impacts surgical planning and contributes to better patient outcomes in pediatric OSA.
Background:
Evidence for drug-induced sleep endoscopy (DISE) versus multilevel surgery guided by clinical examination is sparse in pediatrics.
Methods:
A retrospective cohort study included all children undergoing DISE for obstructive sleep apnea (OSA) between September 2021 and April 2025 in a tertiary pediatric center. Clinical examination of obstruction sites was performed in consultation, and treatment was proposed. The data were compared against the intraoperative anatomic data collected during DISE and associated procedures.
Objective:
To assess the surgical contribution of DISE compared to clinical examination in consultation.
Results:
Files were analyzed for 240 patients, with a mean age of 6.4±4.6 years. 137 (57%) had type 3 OSA, 7 (3%) type 2, and 96 (40%) type 1. DISE led to changes in surgical strategy in 75% of cases, with 803 procedures performed, compared to 597 planned in consultation (P<0.001). Agreement was satisfactory for partial tonsillectomy, but moderate to weak for surgery in other sites, and especially the tongue base and the laryngeal vestibule. Total anatomic score was significantly higher on DISE than in consultation. Median apnea-hypopnea index (AHI) improved significantly after surgery (P<0.001).
Conclusion:
DISE identified more obstruction sites than clinical examination in consultation, in children with OSA.
Related Concept Videos
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Endoscopic Procedures III: Video Capsule Endoscopy
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Endoscopic Procedures V: ERCP
Patient...
