Drug-induced sleep endoscopy in the identification of obstruction sites causing obstructive sleep apnea-hypopnea

M Demoures-Patris de Breuil1, F Chatelet2, N Leboulanger3

  • 1Service d'Otorhinolaryngologie Pédiatrique, AP-HP, Hôpital Necker-Enfants Malades, 75015 Paris, France.

Insights

Drug-induced sleep endoscopy (DISE) identified more airway obstruction sites than clinical exams in children with obstructive sleep apnea (OSA). This led to significant changes in surgical plans and improved outcomes.

Area of Science:

  • Pediatric Otolaryngology
  • Sleep Medicine
  • Surgical Planning

Background:

  • Limited evidence compares drug-induced sleep endoscopy (DISE) with clinical examination for guiding multilevel surgery in pediatric obstructive sleep apnea (OSA).
  • Accurate identification of obstruction sites is crucial for effective surgical intervention in children with OSA.

Purpose of the Study:

  • To evaluate the surgical contribution of DISE compared to traditional clinical examination in pediatric OSA patients.
  • To determine if DISE alters surgical strategy and improves outcomes compared to clinical assessment alone.

Main Methods:

  • Retrospective cohort study of 240 children with OSA undergoing DISE.
  • Comparison of pre-operative clinical examination findings with intraoperative anatomic data from DISE.
  • Analysis of surgical strategy changes and post-operative apnea-hypopnea index (AHI) improvement.

Main Results:

  • DISE prompted surgical strategy changes in 75% of cases, increasing planned procedures from 597 to 803.
  • Agreement between DISE and clinical exam was moderate to weak for most sites, especially tongue base and laryngeal vestibule.
  • DISE revealed a significantly higher total anatomic obstruction score and led to significant AHI improvement post-surgery.

Conclusions:

  • DISE is superior to clinical examination in identifying multiple obstruction sites in children with OSA.
  • DISE significantly impacts surgical planning and contributes to better patient outcomes in pediatric OSA.
Abstract

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