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Spine surgery research: on and beyond current strategies
Wilco C H Jacobs1, Moyo C Kruyt, Ab J Verbout
1Department of Neurosurgery, Leiden University Medical Centre (LUMC), Leiden, The Netherlands. wch.jacobs@gmail.com
Summary
Systematic reviews in spinal surgery need improvement in design and reporting. Enhancing clinical trials and review methodologies can improve evidence gathering for spinal treatments.
Area of Science:
- Spinal Surgery
- Evidence-Based Medicine
- Systematic Literature Review
Background:
- Systematic reviews are crucial in evidence-based medicine.
- Current systematic reviews in spinal surgery have areas for improvement in design and reporting.
Purpose of the Study:
- To identify and discuss key issues relevant to systematic reviews in spinal surgery.
- To offer guidance for improving the design and execution of systematic literature reviews in this field.
Main Methods:
- Inferred guidance from practical experience with systematic reviews and meta-analyses in spinal surgery.
- Focus on practical application and learning from past systematic reviews.
Main Results:
- Clinical trials in spinal surgery face design and conduct challenges, impacting evidence appraisal.
- Prioritize comparing new treatments against the gold standard.
- Thorough data presentation, including subgroups and follow-up, is essential for rigorous systematic reviews.
Conclusions:
- Improving the collection of clinical effectiveness data in spinal surgery is possible at both study and review levels.
- Comparative studies can serve as valuable alternatives to randomized controlled trials for assessing treatment effectiveness.
- This work aims to support scientific endeavors in spinal surgery research.