Oral Candida colonization and candidiasis in patients with psoriasis
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Updated: May 18, 2026
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Published on: March 1, 2024
Ahmad A Bedair1, Azmi M G Darwazeh, Mustafa M Al-Aboosi
1Zarqa Governate Health Directorate, Ministry of Health, Jordan.
Objectives:
The objective of this study was to investigate oral Candida colonization and candidosis in a group of patients with psoriasis and controls.
Study Design:
A total of 100 patients with psoriasis and matched controls underwent the concentrated oral rinse test for Candida isolation. Candida species were identified by the VITEK 2 Identification System. Categorical variables were evaluated using the χ(2) test. The median Candida count was compared using the Mann-Whitney U test.
Results:
Oral candidiasis was diagnosed in 3% of the patients with psoriasis. The Candida count and prevalence were significantly higher in the patients with psoriasis compared with controls (69% vs 44%, P < .001), but with no relationship to the severity or treatment of psoriasis. Oral Candida was significantly higher in late-onset (at age ≥30 years) compared with early-onset psoriasis (at age <30 years).
Conclusions:
Patients with psoriasis have increased oral Candida colonization and candidiasis. Further studies are needed to clarify the predisposing factor(s) for oral Candida in patients with psoriasis.
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