Related Experiment Video
Updated: May 18, 2026
10:46
Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
Doppler optical coherence tomography of retinal circulation
Ou Tan1, Yimin Wang, Ranjith K Konduru
1Department of Ophthalmology, Oregon Health and Science University, OR, USA.
Journal of Visualized Experiments : Jove
|October 2, 2012
Summary
Noncontact optical coherence tomography (OCT) measures retinal blood flow using Doppler shifts. This technology offers repeatable, rapid measurements for managing glaucoma and other retinal diseases.
Area of Science:
- Ophthalmology
- Medical Imaging
- Biomedical Engineering
Background:
- Noncontact retinal blood flow measurement is crucial for diagnosing and managing various eye conditions.
- Current methods may have limitations in speed, repeatability, or accessibility.
Purpose of the Study:
- To develop and validate a novel method for noncontact, repeatable retinal blood flow measurement using Fourier-domain optical coherence tomography (OCT).
- To assess the utility of this method in clinical applications, particularly for glaucoma management.
Main Methods:
- Utilized a Fourier-domain OCT system with a circumpapillary double circular scan (CDCS) protocol.
- Employed a double-angle scanning strategy to ensure accurate Doppler angle acquisition.
- Developed semi-automated software (DOCTORC) to calculate total retinal blood flow, vessel cross-sectional area, and average blood velocity.
Main Results:
- Achieved good reproducibility for total retinal blood flow measurements (<10% variation between graders and methods).
- Demonstrated a strong correlation between OCT retinal blood flow measurements and visual field loss in glaucoma patients (R(2)>0.57).
Conclusions:
- Doppler OCT provides a rapid, noncontact, and repeatable method for measuring total retinal blood flow.
- This technology has the potential to significantly improve the clinical assessment and management of glaucoma and other retinal diseases.
Related Concept Videos
01:19Assessing Blood pressure using a doppler ultrasound
To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
01:19Imaging Studies VII: Vascular Imaging
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...