[Newly development of phosphate binders in hyperphosphatemic patients with kidney dysfunction]
Shigeo Negi1, Shintaro Yamanaka, Daisuke Koreeda
1Division of Nephrology, Department of Internal Medicine, Wakayama Medical University, Japan.
Clinical Calcium
|October 2, 2012
Summary
Hyperphosphatemia is a common complication in chronic kidney disease patients. Phosphate binders are essential for managing serum phosphate levels when diet and dialysis are insufficient.
Area of Science:
- Nephrology
- Cardiovascular Medicine
- Pharmacology
Context:
- Hyperphosphatemia is a frequent complication in chronic kidney disease (CKD) patients.
- Elevated serum phosphate is an independent risk factor for cardiovascular disease and mortality in hemodialysis patients.
- Standard treatments like dietary phosphate restriction and dialysis are often insufficient to normalize phosphate levels.
Purpose:
- To review the development and details of phosphate binders.
- To provide recommendations for clinical practice in managing hyperphosphatemia.
Summary:
- Phosphate binders are crucial for managing hyperphosphatemia in dialysis patients.
- This review covers the evolution and application of phosphate binders.
- Clinical practice recommendations are discussed.
Impact:
- Improved management of hyperphosphatemia in CKD patients.
- Potential reduction in cardiovascular complications and mortality associated with hyperphosphatemia.
- Guidance for clinicians on optimal use of phosphate binders.
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