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Updated: May 18, 2026
10:39
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Pathophysiology of migraine.
1Headache Group, Department of Neurology, University of California, San Francisco, CA, USA.
Annals of Indian Academy of Neurology
|October 2, 2012
Summary
Migraine, a disabling brain disorder, involves changes in the brain's sensory systems. Understanding these alterations is key to developing better treatments for this common neurological condition.
Area of Science:
- Neuroscience
- Neurology
- Pain Research
Background:
- Migraine is a prevalent and disabling neurological disorder.
- Current understanding of migraine pathophysiology is advancing.
- Cranial pain pathways and central nervous system modulation are critical areas of study.
Purpose of the Study:
- To elucidate the underlying mechanisms of migraine.
- To investigate the role of specific brain systems in migraine development.
Main Methods:
- Analysis of the anatomy and physiology of cranial pain-producing structures.
- Evaluation of central nervous system modulation of sensory input.
Main Results:
- Migraine is associated with alterations in sub-cortical aminergic sensory modulatory systems.
- These systems widely influence brain function.
Conclusions:
- Migraine pathophysiology involves dysregulation of widespread brain networks.
- Targeting aminergic sensory modulatory systems may offer therapeutic strategies for migraine.
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