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Updated: May 18, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
Published on: January 28, 2014
Circulating biomarkers
L Badimon1, J C Romero, J Cubedo
1Cardiovascular Research Center, CSIC-ICCC, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, Barcelona, Spain. lbadimon@csic-iccc.org
Insights
New biomarkers aid in preventing cardiovascular diseases (CVD) by identifying at-risk individuals and monitoring disease progression. This review explores recently discovered CVD biomarkers and their clinical applications for improved diagnosis and prognosis.
Area of Science:
- Cardiology
- Biomarker Discovery
- Preventive Medicine
Background:
- Cardiovascular diseases (CVD) are a major global cause of mortality.
- Emerging biomarkers offer potential for primary CVD prevention and risk stratification.
- Current biomarkers include inflammatory, endothelial, neurohormonal, ischemia, and necrosis markers.
Purpose of the Study:
- To review recently discovered biomarkers for cardiovascular diseases.
- To discuss the clinical applications of these novel biomarkers.
- To highlight the importance of new biomarkers for enhancing CVD diagnosis and prognosis.
Main Methods:
- Literature review of recent scientific publications.
- Analysis of studies on novel cardiovascular biomarkers.
- Synthesis of information on clinical utility and applications.
Main Results:
- Several new biomarkers show promise in CVD risk assessment.
- Biomarkers are crucial for identifying individuals at risk and monitoring disease.
- Novel markers can improve diagnostic and prognostic accuracy in CVD.
Conclusions:
- Continued research into novel biomarkers is essential for advancing CVD prevention.
- Biomarkers play a vital role in personalized cardiovascular risk management.
- The clinical application of new biomarkers promises to enhance patient outcomes in CVD.
Abstract:
Cardiovascular diseases (CVD) remain a leading cause of death worldwide. In the past years new biomarkers have drawn the clinician's attention for their use in primary prevention and in the identification of individuals at cardiovascular risk. Biomarkers also provide information on the progression and possible recurrence of cardiovascular events, and include inflammatory markers (C-reactive protein and interleukin-18), endothelial dysfunction markers (intercellular adhesion molecule-1 and vascular cell adhesion molecule-1), neurohormonal markers (brain natriuretic peptide and copeptine), ischemia biomarkers (apolipoprotein J) and necrosis markers (troponins). Although biomarkers provide utility for predicting cardiovascular risk, the identification and characterization of new biomarkers to achieve increasing diagnosis and prognostic efficiency in CVD prevention is of high clinical interest. In this review we will discuss on recently discovered biomarkers and their clinical applications.
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