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i(12p) in a malignant ovarian tumor
F Speleman1, C De Potter, P Dal Cin
1Department of Medical Genetics, University Hospital Gent, Belgium.
Cancer Genetics and Cytogenetics
|March 1, 1990
Summary
The isochromosome 12p (i(12p)) marker was found in a female ovarian germ cell tumor, specifically a yolk sac tumor. This finding suggests the i(12p) marker may play a role in the development of female germ cell tumors, warranting further research.
Area of Science:
- Cytogenetics
- Gynecologic Oncology
- Pathology
Background:
- The isochromosome 12p (i(12p)) is a known cytogenetic abnormality.
- i(12p) is characteristically associated with male germ cell tumors.
- The presence and role of i(12p) in female germ cell tumors remain less understood.