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Related Concept Videos

Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Seizures ll: Types01:19

Seizures ll: Types

Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...

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Updated: May 18, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
09:57

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

Published on: September 20, 2024

Mesial frontal lobe epilepsy.

Kanjana Unnwongse1, Tim Wehner, Nancy Foldvary-Schaefer

  • 1Department of Neurology, Prasat Neurological Institute, Bangkok, Thailand.

Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society
|October 3, 2012
PubMed
Summary
This summary is machine-generated.

Mesial frontal lobe epilepsies present diagnostic challenges due to subtle clinical and EEG features. However, epilepsy surgery offers significant benefits for patients with mesial frontal lobe epilepsy.

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Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe
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Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

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Last Updated: May 18, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
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Published on: September 20, 2024

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe
06:04

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Published on: August 16, 2024

Area of Science:

  • Neurology
  • Epileptology

Background:

  • Mesial frontal lobe epilepsies (FLE) are challenging to diagnose.
  • They originate from the anterior cingulate gyrus or supplementary sensorimotor area.
  • Lack of clear lateralizing/localizing features on clinical semiology and scalp EEG complicates diagnosis.

Purpose of the Study:

  • To review the diagnostic challenges and treatment outcomes for mesial FLE.
  • To highlight the benefits of epilepsy surgery for this patient group.

Main Methods:

  • Review of clinical semiology.
  • Analysis of electroencephalographic (EEG) recordings.
  • Discussion of advanced neurophysiologic techniques (e.g., electrical source imaging, MEG, EEG/fMRI, high-frequency oscillations).

Main Results:

  • Mesial FLE often lacks distinct lateralizing or localizing features.
  • Unique semiologic features have been identified in recent literature.
  • Few studies have applied advanced neurophysiologic techniques to mesial FLE.

Conclusions:

  • Despite diagnostic difficulties, patients with mesial FLE experience comparable or superior outcomes with epilepsy surgery.
  • Further research into advanced neurophysiologic techniques may improve diagnosis and treatment.