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Updated: May 18, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Impact of neonatal intensive care on late preterm infants: developmental outcomes at 3 years
Jennifer E McGowan1, Fiona A Alderdice, Jacqueline Doran
1School of Nursing and Midwifery, Queen's University Belfast, Medical Biology Centre, 97 Lisburn Rd, Belfast BT9 7BL, UK. jmcgowan10@qub.ac.uk
Insights
Late preterm infants (LPIs) who received intensive care (IC) showed no significant differences in cognitive, motor, or language development at age 3. These findings offer reassurance for parents and clinicians regarding the long-term outcomes for LPIs.
Area of Science:
- Neonatal Medicine
- Developmental Pediatrics
- Perinatal Health
Background:
- Late preterm infants (34-36 weeks' gestation) represent a significant portion of preterm births and neonatal admissions.
- The developmental trajectory of late preterm infants (LPIs) following neonatal intensive or high-dependency care (IC) requires further investigation.
Purpose of the Study:
- To assess the impact of neonatal intensive care (IC) on the developmental outcomes of late preterm infants (LPIs) at 3 years of age.
- To compare cognitive, motor, language skills, and growth in LPIs with and without a history of IC.
Main Methods:
- A cohort study of 225 late preterm infants born in Northern Ireland in 2006.
- Comparison of developmental outcomes (cognitive, motor, language) using Bayley Scales of Infant and Toddler Development (3rd Ed.) and growth parameters (height, weight) between LPIs who received IC and those who did not.
Main Results:
- Infants receiving IC had higher risk factors including earlier gestation (34 weeks), lower birth weight, and lower Apgar scores.
- At 3 years, no significant differences were observed in cognitive, motor, or language skills between LPIs who received IC and the control group.
- Growth measurements also showed no significant differences between the two groups.
Conclusions:
- Late preterm infants (LPIs) who received neonatal intensive care (IC) demonstrated comparable developmental and growth outcomes at 3 years of age, despite increased perinatal risks.
- The findings provide reassuring data for parents and clinicians regarding the long-term development of LPIs, even after intensive care.
- The study highlights the lack of routine follow-up for LPIs post-IC, underscoring the need for continued monitoring and support.
Background:
Late preterm infants (LPIs) (34-36 weeks' gestation) account for up to 75% of preterm births and constitute a significant proportion of all neonatal admissions. This study assessed the impact of neonatal intensive or high-dependency care (IC) on developmental outcomes of LPIs at 3 years of age.
Methods:
This cohort study included 225 children born late preterm in Northern Ireland during 2006. Children born late preterm who received IC were compared with children born late preterm who did not receive IC. Cognitive, motor, and language skills were assessed by using the Bayley Scales of Infant and Toddler Development, Third Edition. Growth was assessed by using anthropometric measures of height and weight.
Results:
LPIs who received IC were more often less mature (34 weeks' gestation), with lower birth weight (≤ 2500 g) and Apgar scores (<7 at 5 minutes) compared with the control group. They were more often born by cesarean delivery and more likely to have received resuscitation at birth. At 3 years of age, children born late preterm who received IC demonstrated similar cognitive, motor, and language skills compared with children in the control group. Measurements of growth also did not differ significantly between groups.
Conclusions:
Despite having increased maternal, perinatal, and neonatal risk factors, there were no significant differences in early childhood development between LPIs who received IC and those who did not. LPIs do not receive routine follow-up after IC and this study provides useful and reassuring data for parents and clinicians on the longer-term outcome of this infant group.
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