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A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis
Published on: September 10, 2014
Ultralow voltage, OTFT-based sensor for label-free DNA detection
1Dipartimento di Ingegneria Elettrica ed Elettronica, Università di Cagliari, Italy.
Advanced Materials (Deerfield Beach, Fla.)
|October 3, 2012
Abstract:
An organic ultralow voltage field effect transistor for DNA hybridization detection is presented. The transduction mechanism is based on a field-effect modulation due to the electrical charge of the oligonucleotides, so label-free detection can be performed. The device shows a sub-nanometer detection limit and unprecedented selectivity with respect to single nucleotide polymorphism.

