Related Experiment Video
Updated: Aug 8, 2026
07:54
Cholesterol Efflux Assay
Published on: March 6, 2012
A comparison of results for cholesterol in human serum obtained by the Reference Method and by the Definitive Method
P Ellerbe1, G L Myers, G R Cooper
1Organic Analytical Research Division, National Institute of Standards and Technology, Gaithersburg, MD 20899.
Clinical Chemistry
|February 1, 1990
Abstract:
Here we compare the Reference Method (I) and the Definitive Method (II) for measurement of cholesterol in serum. For pure cholesterol solutions, values by I agree with values by II, but for fresh, frozen, or lyophilized sera, values by I average 1.6% higher than values by II. We conclude that an undetected interference is associated with I. However, the observed difference does not diminish the usefulness of I as an accuracy base for cholesterol measurements, because it is clinically insignificant at present.
